Jessie A.G.L. van Buggenum

The paper shows that combining three inhibitors represses B-cell signaling more effectively than single inhibitors in diffuse large B-cell lymphoma.

This paper introduces QuRIE-seq to simultaneously measure RNA and intracellular epitopes, demonstrating its ability to track B-cell receptor pathway activation and drug response over time.

The paper introduces RAID, a method to analyze both transcriptomes and intracellular phosphoproteins from fixed single cells, showing its ability to detect heterogeneity in cellular responses.

The paper uses single-cell ID-seq to identify BMP signaling as a driver of late-stage epidermal differentiation by analyzing phospho-specific epitopes and transcription factors.

The paper introduces ID-seq, a technology that measures multiple molecular and cellular phenotypes in parallel, and uses it to study kinase inhibitor effects on human epidermal stem cells.