BiophysicsbioRxivPreprint
Bound or unbound: Mapping and monitoring receptor oligomerization using time-resolved fluorescence
Annemarie Greife, R Liu, Paul S. Köhler…·Thomas-Otavio Peulen
This paper develops a framework to quantify protein oligomerization in living cells using fluorescence lifetime and anisotropy imaging, validated with GPCRs and applicable to drug discovery.