Thomas-Otavio Peulen

The paper quantifies mRNA and siRNA payload in lipid nanoparticles using fluorescence microscopy and FCS, showing size-dependent payload and coencapsulation dynamics.

This study investigates FoxP1 assembly and nuclear organization, revealing that its leucine-zipper and Forkhead domains antagonistically regulate complex formation and DNA binding.

This paper introduces a minimalistic 3D-printed setup for single-molecule FRET using blue-green dyes and photostabilizers, demonstrating its effectiveness for conformational studies.

This paper develops a framework to quantify protein oligomerization in living cells using fluorescence lifetime and anisotropy imaging, validated with GPCRs and applicable to drug discovery.