Author

Paula Pezzuto

Primary ORCID profile (0000-0001-9570-8244 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Paula PezzutoiD1 paper · Universidade Federal do Rio de Janeiro

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:development & morphogenesis· 1 Assay:metagenomics· 1 Organism:mouse· 1

Frequent Co-Authors

Amilcar Tanuri· 3 shared Loraine Campanati· 2 shared Renato Santana de Aguiar· 2 shared Rodrigo Delvecchio· 2 shared Alves de Melo Cleonice Bento· 1 shared Ana Luiza Chaves Valadão· 1 shared Ana Luiza Valadao· 1 shared Ana Luiza Valadão· 1 shared

Activity by Year

2016-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

Amilcar Tanuri

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Reactivation of latent HIV-1 in vitro using an alcoholic extract from Euphorbia umbellata (Euphorbiaceae) latex.

Ana Luiza Chaves Valadão, Paula Pezzuto, Viviane A. Oliveira Silva, Barbara Simonson Gonçalves, Átila Duque Rossi, Rodrigo Delvecchio da Cunha, Antonio Carlos Siani, João Batista de Freitas Tostes, Marcelo Trovó, Paulo Damasco, Gabriel Gonçalves, Rui Manuel Reis, Renato Santana de Aguiar, Alves de Melo Cleonice Bento, Amilcar Tanuri

This study identifies phorbol esters in Euphorbia umbellata latex that reactivate latent HIV in human PBMCs and SIV in non-human primate CD4+ T cells via NF-kB activation.

bioRxiv · May 3, 2018 · PreprintMicrobiology

Chloroquine inhibits Zika Virus infection in different cellular models

Rodrigo Delvecchio, Luiza M Higa, Paula Pezzuto, Ana Luiza Valadao, Patricia P Garcez, Fabio L Monteiro, Erick C Loiola, Stevens Rehen, Loraine Campanati, Renato Santana de Aguiar, Amilcar Tanuri

This study shows chloroquine inhibits Zika virus infection in multiple cell models, reduces virus production and cell death without cytotoxicity, suggesting it as a potential therapeutic candidate.

bioRxiv · May 2, 2016Microbiology

The Impact of African and Brazilian Zika virus isolates on neuroprogenitors

Loraine Campanati, Luiza M. Higa, Rodrigo Delvecchio, Paula Pezzuto, Ana Luiza Valadão, Fábio L. Monteiro, Grasiella M. Ventura, Carla Veríssimo, Ana M. Bispo De Filippis, Renato S. Aguiar, Amilcar Tanuri

This study compares the effects of African and Brazilian Zika virus isolates on murine neuroprogenitors, finding the Brazilian isolate causes more severe inhibition of neurite extension and differentiation.

bioRxiv · Apr 20, 2016 · PreprintMicrobiology