Engineering fluoroacetate dehalogenase by growth-based selections to degrade non-natural organofluorides
Suzanne C. Jansen, Pauline van Beers, Clemens Mayer
This study engineers fluoroacetate dehalogenase (FAcD) variants to degrade non-natural organofluorides using growth-based selections, identifying improved activities and an inhibition pathway.
bioRxiv · Jul 16, 2025 · PreprintSynthetic Biology