Author

Suzanne C. Jansen

University of GroningenORCID 0000-0002-2507-9072Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Research Focus:perturbation response prediction· 1 Research Focus:protein design· 1

Frequent Co-Authors

Clemens MayeriD· 4 shared Cristina DuraniD· 1 shared Henriëtte J. RozeboomiD· 1 shared Houdijn Beekhuis· 1 shared Luis F. GuerraiD· 1 shared Manuel M. MülleriD· 1 shared Pauline van Beers· 1 shared Rudy RubiniiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 17 mutual co-author links

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4 shared papersSynthetic Biology

Clemens MayerORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Substituting a conserved histidine alleviates difluoroacetate-dependent isoaspartate formation in a fluoroacetate dehalogenase

Suzanne C. Jansen, Luis F. Guerra, Cristina Duran, Manuel M. Müller, Sílvia Osuna, Clemens Mayer

This study identifies a conserved histidine residue critical for fluoroacetate dehalogenase activity on difluoroacetate and shows substitutions enhance its catalytic efficiency.

bioRxiv · Sep 18, 2026 · PreprintBiochemistry

Engineering fluoroacetate dehalogenase by growth-based selections to degrade non-natural organofluorides

Suzanne C. Jansen, Pauline van Beers, Clemens Mayer

This study engineers fluoroacetate dehalogenase (FAcD) variants to degrade non-natural organofluorides using growth-based selections, identifying improved activities and an inhibition pathway.

bioRxiv · Jul 16, 2025 · PreprintSynthetic Biology

A robust life-or-death selection platform for enzyme evolution

Suzanne C. Jansen, Clemens Mayer

This paper introduces a life-or-death selection platform for enzyme evolution that identifies highly efficient biocatalysts through serial passaging of carbamoylase variants.

bioRxiv · Oct 9, 2023 · PreprintSynthetic Biology

Selecting better biocatalysts by complementing recoded bacteria

Rudy Rubini, Suzanne C. Jansen, Houdijn Beekhuis, Henriëtte J. Rozeboom, Clemens Mayer

This paper describes an in vivo selection strategy using recoded bacteria to evolve biocatalysts with improved catalytic efficiency for non-canonical amino acids.

Angewandte Chemie International Edition · Nov 7, 2022Peer-reviewedSynthetic Biology