Single-cell transcriptomics-guided development of flow cytometric tests predicting chronic myeloid leukemia blast crisis transformation at chronic phase diagnosis
Mengge Yu, Vaidehi Krishnan, Pavithra Shyamsundar, Kian Leong Lee, Florian Schmidt, Xi Ren, Charles T. H. Chuah, Shyam Prabhakar, Verity A Saunders, David T. O. Yeung, Naranie Shanmuganathan, Agnes S. M. Yong, Timothy P. Hughes, S. Tiong Ong
The paper develops flow cytometry tests to predict blast crisis transformation in chronic myeloid leukemia patients using single-cell transcriptomics insights.
bioRxiv · Jan 9, 2025 · PreprintCancer Biology