Elucidating the Mechanism Underlying UBA7-UBE2L6 Disulfide Complex Formation
Pei-Tzu Chen, Jia-Yin Yeh, Jui–Hsia Weng, Kuen‐Phon Wu
The paper determines the cryo-EM structure of the UBA7-UBE2L6 disulfide complex and identifies factors influencing its formation, revealing its role in ISG15 conjugation and immune response regulation.
bioRxiv · Nov 7, 2024 · PreprintBiophysics