VASP Promotes Aortic Valve Calcification by Interacting with FBLIM1 to Activate the Focal Adhesion Pathway
Xiaolin Liu, Qingyuan Xu, Kai Xing, Nan Zhang, Qiang Zheng, Peilei Sun, Rui Li, Wenlong Zhang, Zhaoshui Li, Zhengjun Wang
This study identifies VASP as a key driver of aortic valve calcification through its interaction with FBLIM1 to activate the focal adhesion pathway, promoting calcification and elastin secretion.
bioRxiv · Jul 21, 2026 · PreprintCell Biology