Structural basis of autoantibody binding in Neuromyelitis Optica
Meghna Gupta, Nitesh Khandelwal, Andrew Nelson, Peter Hwang, Sergei Pourmal, Jeffrey L. Bennett, Robert Michael Stroud
This study determines the structural basis of autoantibody binding to aquaporin-4 in NMO, revealing epitope diversity on tetrameric and higher-order assemblies.
Science Advances · Feb 21, 2025Peer-reviewedImmunology