Jeffrey L. Bennett

This study shows microglia drive myelin loss in MS through autoantibodies and BTK signaling, with implications for therapeutic targeting.

This paper introduces an in vivo model for focal astrocyte ablation combined with longitudinal two-photon imaging to study CNS responses to astrocyte loss.

The paper develops a language model to identify MS-associated BCRs by embedding BCR sequences and classifying them for disease association.

This study shows that in a mouse model of NMOSD, demyelination occurs due to off-target complement injury to oligodendrocytes, not directly from astrocyte loss.

This study determines the structural basis of autoantibody binding to aquaporin-4 in NMO, revealing epitope diversity on tetrameric and higher-order assemblies.

The paper shows that mature astrocytes can transform into progenitor-like cells to regenerate astrocytic networks after injury in mice.