Age-related declines in niche self-renewal factors controls testis aging and spermatogonial stem cell competition through Hairless, Imp, and Chinmo
Yu Zheng, Ya‐Chien Lee, Yuting Wang, Pin-Kuan Chiang, Shao-Lun Chang, Hwei‐Jan Hsu, Li‐Sung Hsu, Erika A Bach, Chen‐Yuan Tseng
The paper identifies a regulatory axis involving BMPs, Hairless, Imp, and Chinmo that drives testis aging and spermatogonial stem cell competition in Drosophila.
bioRxiv · May 1, 2025 · PreprintGenetics