Author

Erika A Bach

New York UniversityORCID 0000-0002-5997-4489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

Sneh HarshiD· 2 shared Chen‐Yuan TsengiD· 1 shared Christine A. RushlowiD· 1 shared Hsiao-Yun Liu· 1 shared Hwei‐Jan HsuiD· 1 shared Kari F. LenhartiD· 1 shared Li‐Sung HsuiD· 1 shared Pin-Kuan Chiang· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersDevelopmental Biology

Sneh HarshORCID

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3 papers

Recent·Most cited

Age-related declines in niche self-renewal factors controls testis aging and spermatogonial stem cell competition through Hairless, Imp, and Chinmo

Yu Zheng, Ya‐Chien Lee, Yuting Wang, Pin-Kuan Chiang, Shao-Lun Chang, Hwei‐Jan Hsu, Li‐Sung Hsu, Erika A Bach, Chen‐Yuan Tseng

The paper identifies a regulatory axis involving BMPs, Hairless, Imp, and Chinmo that drives testis aging and spermatogonial stem cell competition in Drosophila.

bioRxiv · May 1, 2025 · PreprintGenetics

The pioneer factor Zelda induces male-to-female somatic sex reversal in adult tissues

Sneh Harsh, Hsiao-Yun Liu, Pradeep Kumar Bhaskar, Christine A. Rushlow, Erika A Bach

The paper shows that the pioneer factor Zelda induces female-specific traits in male Drosophila tissues by upregulating genes that promote feminization and override male identity.

bioRxiv · Mar 26, 2025 · PreprintDevelopmental Biology

Conversion of somatic sex identity in the testis induces female-specific cellular behaviors in the soma and early oocyte specification in the germline

Tiffany V. Roach, Sneh Harsh, Rajiv Sainath, Erika A Bach, Kari F. Lenhart

This study shows that loss of chinmo in Drosophila testis causes somatic cells to adopt female-specific behaviors and influence germline sex identity, leading to early oocyte specification.

bioRxiv · Nov 3, 2024 · PreprintDevelopmental Biology