Predicting Peptide HLA-II Presentation Using Immunopeptidomics, Transcriptomics and Deep Multimodal Learning
Hesham ElAbd, Mareike Wendorff, Tomáš Koudelka, Christian Hentschker, Ann-Kristin Kamps, Christoph Prieß, Lars Wienbrandt, Frauke C. Degenhardt, Tim Alexander Steiert, Petra Bächer, Piyush Mathur, David Ellinghaus, Uwe Völker, Andreas Tholey, Tobias L. Lenz, André Franke
The paper develops PIA-M, a multimodal transformer-based tool for predicting HLA-II peptide presentation, achieving higher accuracy and faster runtime than existing methods.
bioRxiv · Sep 20, 2022 · PreprintBioinformatics