Author

Prachi Nakashe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:non-human primate· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Andi FloryiD· 2 shared Dana W.Y. TsuiiD· 2 shared Daniel S. GrosuiD· 2 shared John A. TynaniD· 2 shared Kristina M. Kruglyak· 2 shared Lisa M. McLennan· 2 shared Rita Motalli-Pepio· 2 shared Allison L. O’KelliD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Andi FloryORCID

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Author profile →

2 papers

Recent·Most cited

Study Design and Interim Analysis of the Cancer Lifetime Assessment Screening Study in Canines (CLASSiC): The First Prospective Cancer Screening Study in Dogs Using Next-Generation Sequencing-Based Liquid Biopsy

Andi Flory, Suzanne Gray, Lisa M. McLennan, Jill M. Rafalko, Maggie A. Marshall, Kate Wotrang, Marissa Kroll, Brian K. Flesner, Allison L. O’Kell, Todd A. Cohen, Carlos A. Ruiz-Pérez, Emily Sandford, Ana G. Clavere-Graciette, Ashley Phelps‐Dunn, Rita Motalli-Pepio, , Daniel S. Grosu

The paper presents an interim analysis of a canine cancer screening study using NGS-based liquid biopsy, showing increased preclinical cancer detection with OncoK9(R) testing.

bioRxiv · Apr 1, 2024 · PreprintGenomics

Blood-based liquid biopsy for comprehensive cancer genomic profiling using next-generation sequencing: an emerging paradigm for noninvasive cancer detection and management in dogs

Kristina M. Kruglyak, Jason Chibuk, Lisa M. McLennan, Prachi Nakashe, Gilberto E. Hernandez, Rita Motalli-Pepio, Donna M. Fath, John A. Tynan, Lauren E. Holtvoigt, Ilya Chorny, Daniel S. Grosu, Dana W.Y. Tsui, Andi Flory

This study shows that blood-based liquid biopsy using next-generation sequencing can detect genomic alterations in dogs with cancer, matching tumor tissue findings and identifying alterations from spatially separated tumor sites.

Frontiers in Veterinary Science · Jul 8, 2021Peer-reviewedGenomics