Tubulin glycylation regulates microtubule-protein interactions that are key for ciliary stability and trafficking
Sanjana Mullick, Chaya Suresh Kumar, Sucheta Dey, Prajwal Koushik, Rayees A. Ganie, Susobhan Mahanty, Minhajuddin Sirajuddin, Sudarshan Gadadhar
This study shows that tubulin glycylation affects ciliary microtubule stability and motor protein interactions, enhancing kinesin-2 activity and protecting microtubules from depolymerization.
bioRxiv · Mar 30, 2026 · PreprintBiochemistry