Inter-Spheroid Proximity and Matrix Remodeling Determine CAF-Mediated Cancer Cell Invasion
Pranav Mehta, Ankur Bordoloi, Cor J. Ravensbergen, M. Kristen David, Wilma E. Mesker, Gerrit‐Jan Liefers, Peter ten Dijke, Pouyan Esmailzadeh Boukany
This study investigates how CAFs drive cancer cell invasion through matrix remodeling and inter-spheroid proximity in a 3D in vitro model of Luminal A breast cancer.
bioRxiv · Apr 24, 2025 · PreprintCancer Biology