Invasive cancer cells soften collagen networks and disrupt stress-stiffening via volume exclusion, contractility and adhesion
Irène Nagle, Margherita Tavasso, Ankur Bordoloi…·Pouyan Esmailzadeh Boukany
This study shows invasive cancer cells alter collagen network mechanics through volume exclusion, adhesion, and contractility, leading to softening and suppression of stress-stiffening.