NAC promotes co-translational folding at the ribosomal tunnel exit
Jaime Santos, Manuel Günnigmann, Radoslaw J. Gora, Marija Iljina, Masa Predin, Ilgin Eser Kotan, Pratiman De, Dhawal Choudhary, Juwon Jang, Frank Tippmann, Nenad Ban, Sander J. Tans, Shu‐ou Shan, Günter Kramer, Bernd Bukau
The paper identifies NAC's role in promoting co-translational folding by interacting with nascent chains at the ribosomal tunnel exit, expanding its known functions in protein biogenesis.
bioRxiv · Aug 2, 2025 · PreprintBiochemistry