Macrophage Migration Inhibitory Factor (MIF)-CD74 Signaling Pathway Mediates Trabecular Meshwork Dysfunction in Glaucoma.
Monu Monu, Lal Krishan Kumar, Prince Kumar, Gulab S Zode, Pawan Kumar Singh
This study identifies MIF-CD74 signaling as a regulator of trabecular meshwork dysfunction in glaucoma, showing its role in suppressing Blimp-1 and promoting ECM remodeling and cytoskeletal changes.
bioRxiv · Mar 20, 2026 · PreprintImmunology