Author

Priya Periakaruppan

University of Minnesota

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Courtney Baar· 1 shared Deepali Sachdev· 1 shared Katelyn J. HoffiD· 1 shared Valeria C. Torres IrizarryiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

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1 shared paperCancer Biology

Courtney Baar

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1 paper

Recent·Most cited

In vivo acquired resistance to tamoxifen is associated with irreversible loss of IGF1R, upregulation of insulin receptor and enhanced sensitivity to insulin

Katelyn J. Hoff, Priya Periakaruppan, Courtney Baar, Valeria C. Torres Irizarry, Deepali Sachdev

This study shows that in vivo tamoxifen resistance in HR+ breast cancer is linked to IGF1R loss, IR-A upregulation, and increased insulin sensitivity, suggesting potential therapeutic strategies targeting IR-A.

bioRxiv · Jun 11, 2026 · PreprintCancer Biology