Katelyn J. Hoff

This study shows that in vivo tamoxifen resistance in HR+ breast cancer is linked to IGF1R loss, IR-A upregulation, and increased insulin sensitivity, suggesting potential therapeutic strategies targeting IR-A.

The paper investigates the role of α-tubulin helix 11 in tubulin heterodimer conformation and microtubule dynamics, showing its impact on disease and evolutionary conservation.

The paper shows that reduced Tuba1a impairs axon guidance but supports neuronal migration, revealing TUBA1A's role in microtubule dynamics during neurodevelopment.