Osteoprotegerin-Enabled Immune Evasion by Pathological Adipose Stromal Cells Drives Metabolic Dysfunction in Obesity
Hara Apostolopoulou, Yao Wang, William Reid Bolus, Radha Dutt Singh, Arjan Bains, Priyadarshini Bahadure, Kavya Gupta, Suneil K. Koliwad, Anil Bhushan
This study identifies senescent adipose progenitor cells (sAPCs) in obesity that produce osteoprotegerin (OPG), enabling immune evasion and metabolic dysfunction.
bioRxiv · Jan 13, 2026 · PreprintImmunology