Author

Arjan Bains

University of California, San FranciscoORCID 0000-0001-8391-4374Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Anil BhushaniD· 2 shared Hara Apostolopoulou· 2 shared Yao WangiD· 2 shared Ajay V. MakeriD· 1 shared David L. GibbsiD· 1 shared Im‐Hong SuniD· 1 shared James Morgan GardneriD· 1 shared Kavya GuptaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersImmunology

Anil BhushanORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 13, 2026

Osteoprotegerin-Enabled Immune Evasion by Pathological Adipose Stromal Cells Drives Metabolic Dysfunction in Obesity

Hara Apostolopoulou, Yao Wang, William Reid Bolus…·Anil Bhushan

This study identifies senescent adipose progenitor cells (sAPCs) in obesity that produce osteoprotegerin (OPG), enabling immune evasion and metabolic dysfunction.

DOI 10.64898/2026.01.12.698936

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 4, 2025

Blocking Osteoprotegerin Reprograms Cancer Associated Fibroblast to Promotes Immune Infiltration into the Tumor Microenvironment

Yao Wang, Hara Apostolopoulou, Im‐Hong Sun…·Anil Bhushan

This study identifies OPG-secreting CAFs as immunosuppressive stromal cells and shows that blocking OPG promotes immune infiltration and tumor regression in mouse models.

DOI 10.1101/2025.07.04.663190

mouseexperimental assay

𝕏 PostBluesky