Peripheral kappa opioid receptor activation drives cold hypersensitivity in mice
Manish K. Madasu, Loc V. Thang, Priyanka Chilukuri, Sreemathi Palanisamy, Joel S. Arackal, Tayler D. Sheahan, Audra F. Bryan, Richard A. Houghten, Jay P. McLaughlin, Jordan G. McCall, Ream Al‐Hasani
This study identifies a role for peripheral kappa opioid receptors in driving cold hypersensitivity through modulation of TRPA1 channels in mice.
Journal of Pain · May 1, 2022Peer-reviewedNeuroscience