Ream Al‐Hasani

This study shows that maternal separation stress disrupts noradrenergic signaling in the locus coeruleus, leading to altered coping behaviors in adulthood.

The paper develops a method to detect dynamic changes in enkephalin levels in mice during acute stress, revealing their release and correlation in the nucleus accumbens shell.

This study shows that spared nerve injury in mice does not significantly affect negative affective behaviors in short-term tests but reveals reduced motivation for food rewards in long-term testing.

This paper develops microimmunoelectrodes for electrochemical detection of dynorphin, showing sensitivity in the attomolar range and selectivity over other opioids.

This study identifies a role for peripheral kappa opioid receptors in driving cold hypersensitivity through modulation of TRPA1 channels in mice.

This study compares long-term effects of in utero versus continued postnatal oxycodone exposure in mice, finding sex-dependent changes in sensory and reward processing but no major behavioral deficits.

This study examines the effects of in utero and postnatal oxycodone exposure on mouse behavior and development, finding sex-dependent weight changes, altered vocalizations, and sensorimotor delays.

The paper develops a system to measure opioid peptide release in vivo using optogenetics, microdialysis, and mass spectrometry in freely moving rodents.