Staphylococcus aureus uses the bacilliredoxin (BrxAB)/bacillithiol disulfide reductase (YpdA) redox pathway to defend against oxidative stress under infections
N. Linzner, V. V. Loi, V. N. Fritsch, Q. N. Tung, S. Stenzel, M. Wirtz, R. Hell, C. Hamilton, K. Tedin, M. Fulde, H. Antelmann
This study identifies the BrxAB/BSH/YpdA pathway as critical for S. aureus to manage oxidative stress and survive infections by maintaining BSH redox homeostasis.
bioRxiv · May 1, 2019Microbiology