Myeloid-Driven Inflammation in Prodromal Parkinson's Disease
Yoshiaki Yasumizu, M. Elizabeth Deerhake, Jeonghyeon Moon, Nicholas Buitrago-Pocasangre, Anthony Russo, Haowei Wang, Biqing Zhu, John Peter Seibyl, Vijaya Reddy, Qianchang Wang, Karen J Neish, Maria Grazia Spillantini, David A Posner, Menna Ruth Clatworthy, Tomokazu S. Sumida, , David A. Hafler
The paper identifies increased myeloid-driven inflammation in the CNS of prodromal Parkinson's Disease patients, linking gut and CNS immune responses through shared T cell clones.
bioRxiv · May 16, 2025 · PreprintImmunology