Erin E. Longbrake

The paper identifies an intrathecal antibody response to EBV BRRF2 and human antigens in MS, showing cross-reactivity and association with increased IgG synthesis.

The paper identifies increased myeloid-driven inflammation in the CNS of prodromal Parkinson's Disease patients, linking gut and CNS immune responses through shared T cell clones.

This study uses single-cell RNA sequencing to analyze immune changes after B-cell depletion in MS patients, revealing cell type-specific effects on macrophages, monocytes, and T cells.

The paper introduces GMWI2, a gut microbiome health index that improves disease prediction accuracy compared to previous models and traditional diversity indices.

The paper describes how the Yale Generations Project adapted its recruitment, consent, and DNA sample acquisition processes to remote methods during the COVID-19 pandemic, resulting in continued enrollment and sample collection.