Author

Qiong Luo

South China Normal University

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Biology Disciplines

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Genomics· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:Hi-C· 2 Assay:ATAC-seq· 1 Approach:Bayesian inference· 1 Research Focus:genome assembly· 1 Organism:human· 1 Organism:mouse· 1 Approach:simulation· 1

Frequent Co-Authors

Luming MengiD· 3 shared Chenxi WangiD· 1 shared Fu Kit SheongiD· 1 shared Yi Y. ShiiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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3 shared papersGenomics

Luming MengORCID

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3 papers

Recent·Most cited

Topologically associating domains can arise from stochastic folding of heterogeneous fluidlike chromatin

Luming Meng, Fu Kit Sheong, Qiong Luo

This study shows that stochastic folding of fluidlike chromatin with DNA-packing density heterogeneity can form TADs without cohesin-mediated extrusion, and predicts TAD dynamics during T cell differentiation.

bioRxiv · Sep 12, 2023 · PreprintGenomics

Random folding drives the emergence of topologically associating domains in chromatin three-dimensional structure

Luming Meng, Qiong Luo

The paper proposes that random folding of heterogeneous chromatin fibers underlies topologically associating domains (TADs) and shows that a model can predict chromatin reorganization during differentiation.

bioRxiv · Jul 8, 2022 · PreprintGenomics

Si-C: method to infer biologically valid super-resolution intact genome structure from single-cell Hi-C data

Luming Meng, Chenxi Wang, Yi Y. Shi, Qiong Luo

Si-C reconstructs biologically valid super-resolution 3D genome structures from sparse single-cell Hi-C data, revealing cell-to-cell variation and hyperfine chromatin features.

Nature Communications · Jul 16, 2021Peer-reviewedBioinformatics