Molecular BiologyJACC Basic to Translational SciencePeer-reviewed
Structure-based probe reveals the presence of large transthyretin aggregates in plasma of ATTR amyloidosis patients
Rose Pedretti, Lanie Wang, Anna Yakubovska…·Lorena Saelices
The paper develops a peptide probe based on cryogenic electron microscopy structures to detect large transthyretin aggregates in ATTR amyloidosis patients' plasma, revealing previously unknown aggregated species.
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