Author

Anna Yakubovska

Oncode InstituteORCID 0009-0009-4723-2152Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Binh An NguyeniD· 2 shared Lanie WangiD· 2 shared Lorena SaelicesiD· 2 shared Ahmad MasriiD· 1 shared Andrew S. LemoffiD· 1 shared Barbara Kluve‐Beckerman· 1 shared Jaime Vaquer Alicea· 1 shared Jaime Vaquer‐AliceaiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersBiophysics

Binh An NguyenORCID

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2 papers

Recent·Most cited

BiophysicsStructurePeer-reviewedOct 17, 2024

ATTRv-V30M Type A amyloid fibrils from the heart and nerves exhibit structural homogeneity.

Binh An Nguyen, Shumaila Afrin, Anna Yakubovska…·Layla Villalon

This study determines the structure of ATTRv-V30M amyloid fibrils from cardiac and nerve tissues using cryo-EM, finding structural homogeneity across tissues when transthyretin originates from the liver.

18 citationstop 2%

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Molecular BiologyJACC Basic to Translational SciencePeer-reviewedJul 17, 2024

Structure-based probe reveals the presence of large transthyretin aggregates in plasma of ATTR amyloidosis patients

Rose Pedretti, Lanie Wang, Anna Yakubovska…·Lorena Saelices

The paper develops a peptide probe based on cryogenic electron microscopy structures to detect large transthyretin aggregates in ATTR amyloidosis patients' plasma, revealing previously unknown aggregated species.

16 citations

humanexperimental assay

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