Qiqi Ge

The biochemical nature of senile plaques: intracellular destabilized-lysosome-enriched neural processes catabolizing extracellular hemorrhagic amyloid materials

This study investigates senile plaque formation in Alzheimer's disease using immunohistochemistry and fluorescence imaging, finding that Aβ deposition occurs in degenerative neuritic processes with lysosome destabilization and hemorrhage-related markers.

Pathological axonal enlargement in connection with amyloidosis, lysosome destabilization and hemorrhage is a major defect in Alzheimer's disease

This study identifies axonal enlargement linked to amyloidosis, lysosome destabilization, and hemorrhage as a key pathological feature in Alzheimer's disease.

Re-evaluating the nuclear staining on pathological sections in Alzheimer's disease

The paper challenges the accuracy of nuclear staining in Alzheimer's disease by showing that blue autofluorescence from senile plaques can be mistaken for nuclei.