Cell BiologybioRxivPreprint
The biochemical nature of senile plaques: intracellular destabilized-lysosome-enriched neural processes catabolizing extracellular hemorrhagic amyloid materials
Hualin Fu, Jilong Li, Chunlei Zhang…·Cui Daxiang
This study investigates senile plaque formation in Alzheimer's disease using immunohistochemistry and fluorescence imaging, finding that Aβ deposition occurs in degenerative neuritic processes with lysosome destabilization and hemorrhage-related markers.