Sampling Function-Related Metastable States of Proteins With DASH
Jinyin Zha, Zhen Zheng, Jie Zhong, W.K. Wang, Qiancheng Shen, Qiao Li, Mingyu Kenneth Li, Chengwei Wu, Qingjie Xiao, Qiuhan Ren, Nuan Li, Hao Zhang, Xinyi Liu, Li Feng, Wenming Qin, Jian Zhang
DASH samples function-related metastable states of proteins, revealing new folding states and allosteric sites, verified by experiments and crystal structures.
bioRxiv · Dec 25, 2025 · PreprintBioinformatics