Structural and biochemical studies of human PP2A(B55) holoenzyme and ENSA protein complex
Gang Tian, Xiang Zhang, Hongyue Li, Gang Sun, Lulu Xue, Yufeng Yang, Qiyu Mao, Yan Gao, Lei Sun, Guoliang Xu, Zhizhi Wang, Wenqing Xu
This study investigates the structural and biochemical regulation of PP2A(B55) by ENSA, revealing how pENSA inhibits the enzyme and provides insights for inhibitor development.
bioRxiv · Dec 14, 2025 · PreprintBiophysics