Author

Guoliang Xu

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Hongye WangiD· 2 shared Ping HuiD· 2 shared Ruimiao Ma· 2 shared Ruqi Fan· 2 shared Xiaofen WuiD· 2 shared Gang SuniD· 1 shared Gang Tian· 1 shared Hao WangiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersCell Biology

Hongye WangORCID

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3 papers

Recent·Most cited

The non-coding facet of Pink1 mRNA regulates mitochondria homeostasis

Xiaofen Wu, Yuying Liu, Ruimiao Ma, Hongye Wang, Ruqi Fan, Hao Wang, Weili Yang, Xiaojiang Li, Guoliang Xu, Hong Cheng, Ping Hu

The study shows that non-coding Pink1 mRNA regulates mitochondria homeostasis by interacting with YME1L1 to modulate Opa1 processing, independent of its coding function.

bioRxiv · Jan 6, 2026 · PreprintCell Biology

A minor muscle stem cell population functions as metabolic Trojan horse fueling systemic aging by succinate induced epigenetic reprogramming

Xiaofen Wu, Meng Chen, Ruqi Fan, Hongye Wang, Ruimiao Ma, Xiaocui Tang, Hui Wang, Wei Wei, Jiemin Wong, Guoliang Xu, Ping Hu

This study identifies muscle stem cells as drivers of systemic inflammaging through succinate-induced epigenetic reprogramming, linking metabolic dysregulation to aging phenotypes.

bioRxiv · Dec 26, 2025 · PreprintCell Biology

Structural and biochemical studies of human PP2A(B55) holoenzyme and ENSA protein complex

Gang Tian, Xiang Zhang, Hongyue Li, Gang Sun, Lulu Xue, Yufeng Yang, Qiyu Mao, Yan Gao, Lei Sun, Guoliang Xu, Zhizhi Wang, Wenqing Xu

This study investigates the structural and biochemical regulation of PP2A(B55) by ENSA, revealing how pENSA inhibits the enzyme and provides insights for inhibitor development.

bioRxiv · Dec 14, 2025 · PreprintBiophysics