Author

Lei Sun

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-7864-0337Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lei Sun13 papers · George Washington University

Biology Disciplines

Click to filter author papers

Biophysics· 1 Genetics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:rat· 1 Assay:structural biology· 1

Frequent Co-Authors

Bingna Zhou· 1 shared Feifei GuaniD· 1 shared Gang SuniD· 1 shared Gang Tian· 1 shared Guoliang Xu· 1 shared Hongyue LiiD· 1 shared Jiayi LiuiD· 1 shared Jing HuiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenetics

Bingna Zhou

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Structural and biochemical studies of human PP2A(B55) holoenzyme and ENSA protein complex

Gang Tian, Xiang Zhang, Hongyue Li, Gang Sun, Lulu Xue, Yufeng Yang, Qiyu Mao, Yan Gao, Lei Sun, Guoliang Xu, Zhizhi Wang, Wenqing Xu

This study investigates the structural and biochemical regulation of PP2A(B55) by ENSA, revealing how pENSA inhibits the enzyme and provides insights for inhibitor development.

bioRxiv · Dec 14, 2025 · PreprintBiophysics

Impaired bone strength and bone microstructure in a novel early-onset osteoporotic rat model with a clinically relevant PLS3 mutation

Jing Hu, Bingna Zhou, Xiaoyun Lin, Qian Zhang, Feifei Guan, Lei Sun, Jiayi Liu, Ou Wang, Yan Jiang, Weibo Xia, Xiaoping Xing, Mei Li

This study creates a novel rat model with a PLS3 mutation to study early-onset osteoporosis and finds that alendronate and teriparatide improve bone strength and microstructure.

eLife · Apr 21, 2023Peer-reviewedGenetics