Hydroxyl and Trifluoromethyl Radical Carbohydrate Footprinting for Probing Protein Binding Components of Oligosaccharides
Quadrat Yusuph, Sandeep Kumar Misra, Hao Liu, Joshua S. Sharp
This paper introduces a novel method using radical carbohydrate footprinting to identify glycan-protein interactions and map binding interfaces by analyzing oxidation patterns of oligosaccharides.
Analytical Chemistry · Sep 19, 2025Peer-reviewedBiochemistry