In-depth specificity profiling of Pro-Pro endopeptidases (PPEPs) using combinatorial synthetic peptide libraries
B. Claushuis, R. A. Cordfunke, A. H. de Ru, A. Otte, H. C. van Leeuwen, O. I. Klychnikov, P. A. van Veelen, J. Corver, J. W. Drijfhout, P. J. Hensbergen
The paper develops a method combining synthetic peptide libraries and mass spectrometry to profile the specificity of Pro-Pro endopeptidases (PPEPs) and identifies new substrates and specificity patterns.
bioRxiv · Nov 15, 2022 · PreprintBiochemistry