P. A. van Veelen

This study shows that AMPK activation makes human dendritic cells more tolerogenic by altering their metabolism, specifically increasing RALDH activity and changing lipid and glucose metabolism.

This study uses single-cell data to deconvolute bulk RNA-seq samples of AML, showing that differentiation stages can be reconstructed and used to predict drug responses like Venetoclax resistance.

The paper develops a method combining synthetic peptide libraries and mass spectrometry to profile the specificity of Pro-Pro endopeptidases (PPEPs) and identifies new substrates and specificity patterns.

This study investigates how the OA risk allele rs1052429-A affects cartilage matrix deposition through WWP2 upregulation and hypoxia-related genes in a 3D in vitro model.

The paper identifies TAP-independent antigen presentation in healthy cells using a T cell clone and highlights the need for comprehensive testing of healthy cell types to safely target antigens for immunotherapy.

This study maps glycosylation sites of Fc gamma receptor IIIb from neutrophils using LC-MS/MS and identifies donor allotype differences.

The paper generates a panel of APM knockout cell lines to study HLA class I antigen presentation and its role in immune responses.

This paper develops a fluorescent small-molecule probe to monitor UCHL1 activity in live cells and zebrafish embryos, showing specificity for UCHL1 over other DUBs.