Author

R. A. Dick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Organism:virus· 1

Frequent Co-Authors

C. L. Ricana· 2 shared A. Tan· 1 shared C. M. Highland· 1 shared J. A. G. Briggs· 1 shared M. C. Johnson· 1 shared T. D. Lyddon· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBiochemistry

C. L. Ricana

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2 papers

Recent·Most cited

Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by singleparticle cryo-EM

C. M. Highland, A. Tan, C. L. Ricana, J. A. G. Briggs, R. A. Dick

This study uses cryo-EM to determine high-resolution structures of HIV-1 capsid lattices containing hexamers and pentamers, revealing the role of IP6 in pentamer formation and the structure of the lattice bound to the drug GS-6207.

bioRxiv · Dec 2, 2022Biochemistry

Inositol hexakisphosphate (IP6) and inositol pentakisphosphate (IP5) are required for viral particle release of retroviruses belonging to the primate lentivirus genus

C. L. Ricana, T. D. Lyddon, R. A. Dick, M. C. Johnson

This study shows that IP6 and IP5 are essential for HIV-1 and SIV-mac particle release, but not for other retroviruses, and are required in producer cells, not target cells.

bioRxiv · May 21, 2020Microbiology