R. A. Kovall

Cooperative Gsx2-DNA Binding Requires DNA Bending and a Novel Gsx2 Homeodomain Interface

This study investigates how Gsx2 binds DNA cooperatively, revealing structural and thermodynamic mechanisms underlying its dimeric DNA binding and specificity.

Structural and functional studies of the RBPJ-SHARP complex reveal conserved corepressor binding site

This study determines the structure of the RBPJ-SHARP complex and shows that SHARP binding is essential for RBPJ's repressor function in Notch signaling.