Author

R. A. Owens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:fungi (other)· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

B. P. Thornton· 1 shared D. Thomson· 1 shared E. Bignell· 1 shared H. Muhamadali· 1 shared J. Amich· 1 shared J. Scott· 1 shared K. Hollywood· 1 shared L. Tabernero· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMicrobiology

B. P. Thornton

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1 paper

Recent·Most cited

Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence

J. Scott, M. Sueiro-Olivares, B. P. Thornton, R. A. Owens, H. Muhamadali, R. Fortune-Grant, D. Thomson, R. Thomas, K. Hollywood, S. Doyle, R. Goodacre, L. Tabernero, E. Bignell, J. Amich

This paper identifies methionine synthase as a promising antifungal target by showing its essentiality in Aspergillus fumigatus and validates its druggability using a genetic model of established infections.

bioRxiv · Jun 4, 2020Microbiology