Computational structure prediction methods enable the systematic identification of oncogenic mutations
X. Fu, C. Reglero, V. Swamy, J. W. Loh, H. Khiabanian, R. Albero, F. Forouhar, M. Al Quraishi, A. A. Ferrando, R. Rabadan
This paper introduces a computational method to identify oncogenic mutations by integrating evolutionary information and protein structure prediction, demonstrating its effectiveness in pediatric leukemias.
bioRxiv · Nov 18, 2022 · PreprintCancer Biology