Author

R. Amante

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. E. Nibbs· 1 shared A. Kirov· 1 shared B. A. Tannous· 1 shared C. C. da Hora· 1 shared c. E. badr· 1 shared E. Fitzsimons· 1 shared E. Tabet· 1 shared I. Nakano· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. E. Nibbs

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1 paper

Recent·Most cited

Obtusaquinone is a cysteine modifying compound that targets Keap1 for degradation

c. E. badr, C. C. da Hora, A. Kirov, R. Amante, E. Fitzsimons, J. W. Chen, A. E. Nibbs, I. Nakano, E. Tabet, N. Chiu, W. Haas, R. Mazitschek, B. A. Tannous

This study identifies Obtusaquinone as a cysteine-modifying compound that targets Keap1 for degradation, activating the Nrf2 pathway through proteasomal degradation.

ACS Chemical Biology · Apr 27, 2020Peer-reviewedCancer Biology