Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
E. Panizza, B. D. Regalado, F. Wang, I. Nakano, N. M. Vacanti, R. A. Cerione, M. A. Antonyak
The paper identifies NAMPT-containing microvesicles as mediators of radiation resistance in glioma stem cells through proteomic analysis.
bioRxiv · Mar 23, 2022Cancer Biology
Y. Ghochani, A. Sohrabi, S. D. D. Muthukrishnan, R. Kawaguchi, M. Condro, S. Bastola, F. Gao, Y. Qin, J. Mottahedeh, M. L. I. Arispe, N. Rao, D. R. Laks, L. Liau, G. Mathern, S. Goldman, , H. Kornblum
bioRxiv · Oct 1, 2021 · PreprintCancer Biology
J. Wang, M. S. Pavlyukov, D. Yamashita, P. Cheng, Z. Zhang, S.-H. Kim, M. A. Nakano, W. Xie, D. Chen, B. Frett, W.-h. Hu, Y. J. Shin, Y. Lee, V. Goidts, D.-H. Nam, , I. Nakano
This study identifies NEK2-EZH2 signaling as critical for glioblastoma tumor core progression and resistance, and presents a novel inhibitor CMP3a that shows therapeutic potential.
bioRxiv · Dec 1, 2020 · PreprintCancer Biology
D. Yamashita, D. Botta, H. J. Cho, X. Guo, S. Ozaki, V. L. Flanary, I. Sirota, M. Gao, S. Yamaguchi, M. A. Nakano, F. Zhou, H. Zhou, T. Kondo, T. Kunieda, D. Crossman, , I. Nakano
This study identifies clonal subpopulations in glioblastoma core and edge lesions and shows that NAD+ depletion via CD38 inhibition reduces tumor edge formation.
bioRxiv · Nov 26, 2020 · PreprintCancer Biology
S. Bastola, M. S. Pavlyukov, Y. Ghochani, N. Sharma, M. A. Nakano, D. Muthukrishnan, S. Y. Yu, M. S. Kim, A. Sohrabi, N. P. Biscola, D. Yamashita, K. Anufrieva, R. Kawaguchi, Y. Qin, S. K. Seidlits, , H. Kornblum
This study identifies Endocan as an endothelial-secreted ligand for PDGFR alpha that promotes GBM vascularity, radioresistance, and phenotypic diversity.
bioRxiv · Oct 12, 2020 · PreprintCancer Biology
D. Yamashita, V. L. Flanary, R. B. Munk, K. Sonomura, S. Ozaki, R. Kawaguchi, S. Suehiro, S. Bastola, M. S. Pavlyukov, S. Yamaguchi, M. A. Nakano, T. Kunieda, D. Hambardzumyan, T. Kondo, H. Kornblum, , I. Nakano
This study shows that aging reduces neuronal signaling in gliomas, but NAD+ and BDNF can reverse these effects, improving outcomes in older mice.
bioRxiv · Oct 10, 2020 · PreprintCancer Biology
C. Li, H. J. Cho, D. Yamashita, M. Abdelrashid, Q. Chen, S. Bastola, G. Chagoya, G. A. Elsayed, S. Komarova, S. Ozaki, Y. Ohtsuka, T. Kunieda, H. I Kornblum, T. Kondo, D.-H. Nam, I. Nakano
The paper identifies a CD133down/CD109up signature associated with poor prognosis in glioblastoma recurrence and shows PLAGL1 mediates tumor progression through CD109 regulation.
bioRxiv · Sep 14, 2020Cancer Biology
c. E. badr, C. C. da Hora, A. Kirov, R. Amante, E. Fitzsimons, J. W. Chen, A. E. Nibbs, I. Nakano, E. Tabet, N. Chiu, W. Haas, R. Mazitschek, B. A. Tannous
This study identifies Obtusaquinone as a cysteine-modifying compound that targets Keap1 for degradation, activating the Nrf2 pathway through proteasomal degradation.
ACS Chemical Biology · Apr 27, 2020Peer-reviewedCancer Biology