BiochemistrybioRxiv
Measuring Endoplasmic Reticulum Signal Sequences Translocation Efficiency Using the Xbp1 Arrest Peptide
T. Kriegler, A. Magoulopoulou, R. Amate Marchal, T. Hessa
The paper measures the efficiency of ER signal sequences by analyzing translational arrest using an Xbp1 peptide assay, showing efficient sequences undergo a two-phase translocation while inefficient ones experience a single weaker event.
DOI 10.1016/j.chembiol.2018.04.006