Bypass of DNA Interstrand crosslinks by a Rev1-DNA polymerase ζ complex
R. B. Buch, Y. K. Cheun, U. Roy, O. D. Schärer, P. M. Burgers
This study shows that the Rev1-Pol ζ complex is more efficient than Pol ζ alone or Pol η in bypassing ICL damage, with Rev1's structural role being critical for TLS efficiency.
bioRxiv · May 9, 2020 · PreprintBiochemistry