Role of transmembrane helix 6 in substrate recognition of the amino acid transporter MhsT
P. Nissen, M. Quick, R. Blunck, J. Lyons, C. M. T. Neumann, D. Focht, J. A. Javitch, A. Eguskiza, L. Malinauskaite, I. O. Schwarz
The paper investigates how the flexibility of a GMG motif in TM6 of MhsT enables substrate recognition of different amino acid sizes by shaping the binding site.
bioRxiv · Apr 3, 2020 · PreprintBiochemistry